Which of the following enzymes undergoes acid-catalyze zymogen activation in the

Question

Which of the following enzymes undergoes acid-catalyze zymogen activation in the stomach? Trypsinogen Procarboxypeptidase Ribonuclease Chymotrypsinogen None of the above Which of the following is TRUE of glutamate dehydrogenase (GDH)? GDH catalyzes the formation of ammonia destined for the Urea Cycle GDH is a cytoplasmic enzyme that binds to the outer surface of mitochondria. GDH uses NAD in reductive amination of alpha-ketoglutarate. GDH is regulated by arginine and N-acetylglutamate. GDH undergoes enzyme catalyzed adenylylation and deadenylytation.

Explanation / Answer

44) none of the above. The enzyme which is activated by enzyme in the stomach is propepsin which form pepsin on activation

45) GDH catalyses formation of ammonia destined for urea cycle

Glutamate dehydrogenase (GDH) is located in the mitochondria(so not a cytoplasmic enzyme). GDH catalyzes the reversible NAD (P)+-linked oxidative deamination(not reductive deamination) of L-glutamate into alpha ketoglutarate and ammonia .

the ammonia produced in the reverse reaction of GDH is excreted as NH4+ in the urine, by first going through the urea cycle

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