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Use the following diagram from a Nature Review article that outlines +RNA viral

ID: 97414 • Letter: U

Question

Use the following diagram from a Nature Review article that outlines +RNA viral replication to help you answer the activity questions on the next page.

2. After entry, what is the first process labeled “A”? (1 point)

Receptor binding Pro-apoptotic Anti-apoptotic effects effects Entry Shut off host cell (cap- dependent) translation Shut off host cell transcription Polyprotein st Interactions between the virus and the cell cycle Uncoating Viral replication complex Negative strand synthesis 5 dsRNA (latency?) IRES-driven translation strand (genome) 5 3 3' 3' 3 5 Packaging Cell lysis Viral egress

Explanation / Answer

after entry first of all it uncoat form its protein coat then this uncoated rna goes into normal cell and infected rna joins with the genome of uninfected cell and replicate in it then it again packed with protein coat and and goes out of cell and infects other uninfected cells

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