Which of the following statements best describes the induced-fit model of enzyme

Question

Which of the following statements best describes the induced-fit model of enzyme action? In this model, the enzyme changes the shape of a substrate using a cofactor. In this model, the enzyme adjusts it shape to adapt to the shape of the substrate. In this model, the enzyme induces a change of polarity in the substrate that results in bonding. In this model, the enzyme's active site is complementary to the shape of the substrate. In this model, the enzyme's active site chemically reacts with the substrate.

Explanation / Answer

In the Induced-fit model of enzyme action,

B) The enzyme adjusts it shape to adapt to the shape of the substrate.

E) The enzyme’s active sites chemically react with the substrate. The catalytic group (active sites) is believed to weaken the substrate bonds by nucleophilic and electrophilic attack.

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Note:

A) Change in shape of enzyme takes place and not in the substrate shape.

C) No polarity changes in substrate.

D) Enzyme’s active site is complementary to the shape of the substrate. This is the basis of “Lock and Key” model and not of the Induced-fit model.

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