Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

please answer questions 1,2,3,4 Genetically modified organisms (GMOs) are organi

ID: 98010 • Letter: P

Question

please answer questions 1,2,3,4 Genetically modified organisms (GMOs) are organisms in which the genetic material (DNA) has been altered in a manner that does not occur naturally. The technology allows individual genes to be transferred from one organism into another, also between non-related species. Describe two specific examples of a commercially used GMO. What are the benefits of GM foods, in general? What are the main issues of concern for human health? Where do you stand on the use of GM foods?

Explanation / Answer

Ans 1:

1) Corn
Almost 85 perecent of corn grown in the U.S. is genetically modified. Even Whole Foods’s brand of corn flakes was found to contain genetically modified corn. Many producers modify corn and soy so they are resistant to the herbicide glyphosate, which is used to kill weeds.

2) Soy
Soy is the most heavily genetically modified food in the country. The largest U.S. producer of hybrid seeds for agriculture, Pioneer Hi-Bred International, created a genetically engineered soybean, which was approved in 2010. It is modified to have a high level of oleic acid, which is naturally found in olive oil. Oleic acid is a monounsaturated omega-9 fatty acid that may lower LDL cholesterol (traditionally thought of as “bad” cholesterol) when used to replace other fats.

Ans 2: Environmental benefits. Less chemicals, time, machinery, and land are needed forGMO crops and animals, which can help reduce environmental pollution, greenhouse gas emissions, and soil erosion. Enhanced productivity because of GMOs could allow farmers to dedicate less real estate to crops.

Ans 3: POSSIBLE HEALTH CONCERNS

•    Organ failure (rats): A study analyzing the effects of GE foods on mammalian health linked three GE corn varieties to organ failure in rats. The researchers led by Gilles-Eric Séralini of CRIIGEN and the University of Caen in France found new side effects linked with GE corn consumption that were sex- and often dose-dependent. These effects mostly occurred with the kidney and liver, while other effects were noticed in the heart, adrenal glands, spleen and hematopoietic system. The researchers concluded that these data highlight signs of hepato-renal toxicity, possibly due to the new pesticides specific to each GE corn.

•    Glyphosate and birth defects: Research published Aug. 9, 2010 , confirms that glyphosate-based herbicides cause malformations in frog and chicken embryos at doses significantly lower than those used in agricultural spraying and well below maximum residue levels in products currently approved in the European Union. Glyphosate is the active ingredient in Roundup. Publishing the research were researchers led by Professor Andrés Carrasco, director of the Laboratory of Molecular Embryology at the University of Buenos Aires Medical School and member of Argentina’s National Council of Scientific and Technical Research. “The findings in the lab are compatible with malformations observed in humans exposed to glyphosate during pregnancy,” Carrasco reported at a press conference during the 6th European Conference of GMO Free Regions. He explained that most of the safety data on glyphosate herbicides and GE soy were provided by industry and are not independent. Carrasco began researching the embryonic effects of glyphosate after seeing reports of high rates of birth defects in rural areas of Argentina where GE Roundup Ready soybeans are grown in large monocultures sprayed regularly from airplanes.

•    Impacts on animal health. Researchers from Greece reported that animal toxicology studies of GE foods indicate they can have toxic hepatic, pancreatic, renal and reproductive effects. Also, the use of recombinant growth hormones or its expression in animals should be re-examined since it has been shown that it increases IGF-1 which may promote cancer.

•    Serious human health risks. The American Academy of Environmental Medicine, in a 2009 Genetically Modified Foods Position Paper , called for a moratorium on GE foods and warned that “GM foods pose a serious health risk in the areas of toxicology, allergy and immune function, reproductive health, and metabolic, physiologic and genetic health.” This position paper cites animal studies that indicate such health risks associated with GM food consumption as infertility, immune dysregulation, accelerated aging, dysregulation of genes associated with cholesterol synthesis, insulin regulation, cell signaling and protein formation, and changes in the liver, kidney, spleen and gastrointestinal system. “Because of the mounting data, it is biologically plausible for genetically modified foods to cause adverse health effects in humans,” the report notes, listing citations for numerous peer-reviewed studies as backup.

•    Bt toxin in human blood. Most recently, a study accepted for publication in the journal Reproductive Toxicology conducted by scientists at the University of Sherbrooke in Canada reports the presence of Bt toxin, widely used in GE crops, in human blood. Although scientists and multinational corporations promoting GE crops have maintained that Bt toxin poses no danger to human health as the protein, Cry1Ab, breaks down in the human gut, the findings from this study show this does not happen. Instead, it was found circulating in the blood of pregnant and non-pregnant women. The study also detected the toxin in fetal blood. Cry1Ab toxin was detected in 93 percent and 80 percent of maternal and fetal blood samples, respectively, and in 69 percent of tested blood samples from non-pregnant women.

Ans 4: Genetically modified (GM) crops that can withstand pests and droughts. Genetic modification in crops involves altering a seed’s DNA in order to, say, increase its resistance to pests and insects. These changes can mean a huge boost to productivity and overall food supply. In the West, GM foods are fairly common; the US, for instance, cultivates eight crops using this technology. The median estimate for future growth sees the world population reaching 9.7 billion in 2050 and 11.2 billion in 2100. Therefore, GM crops are the only way to feed them all.