For this question, the one marked is wrong. Question 7 (1 point) The processes o
ID: 983795 • Letter: F
Question
For this question, the one marked is wrong.
Question 7 (1 point) The processes of DNA replication and RNA transcription are similar in some respects and different in others. Select the statements below that describe BOTH DNA replication and RNA transcription. The direction of polymerization is 5' to 3 The direction of enzyme movement on the template strand is 3' to 5' The mechanism of reaction is attack by the 3'OH group of the pentose on the a-phosphate of an incoming nucleoside triphosphate O The process includes its own 3' to 5' exonuclease proofreading mechanism A specific region of the DNA is recognized and bound by the polymerase. O The The process requires a primer.Explanation / Answer
7) Similarities of DNA replication and RNA transcription:
1. Both processes use polymerases
Yes the polymerase types used in each case are different, But they still do use polymerases
2. Replication and transcription both take place in the nucleus using DNA as the template
3. They both use base pairing during the processes.
4. both process starts with the unwinding of the DNA.
5. Both require the aid of many regulatory and functional proteins in order ro effectively transcribe or replicate.
Differences
RNA polymerase (RNAP or RNApol) is an enzyme that produces RNA
.
Unlike DNA replication, transcription does not need a primer to start.
RNA polymerase simply binds to the DNA and, along with other cofactors, unwinds the DNA to create an initiation bubble so that the RNA polymerase has access to the single-stranded DNA template
However, RNA Polymerase does require a promoter like sequence.
A DNA polymerase is an enzyme that catalyzes the polymerization of deoxyribonucleotides into a DNA strand. During replication, Once strands are separated, RNA primers are created on the template strands and DNA polymerase extends these to create newly synthesized DNA.
comparisions
DNA replication involves unzipping the double helix with helicase and attaching a RNA primer with primase, and DNA polymerase III attaches nucleotides to the primers on the leading strand, and the lagging strand is built with okazaki fragments that are joined together with DNA ligase. Topoisomerase straightens out the DNA strand as it is being unzipped and single-strand binding proteins hold the DNA template in place while it is being copied.
Transcription involves the the building of an mRNA and does not require helicase to unzip the DNA double helix. In the initiation step, RNA polymerase attaches to the promoter region and the DNA strands unwind and RNA polymerase transcribes the mRNA strand, called the elongation phase. The mRNA strand comes out while it is still being transcribed, and the DNA double helix is rewound after RNA polymerase passes it. In the termination stage, the RNA transcript (mRNA) is released and the RNA polymerase detaches from the DNA strand.
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