How would a mutation that reduced uracil formation affect DNA replication? A) Th

Question

How would a mutation that reduced uracil formation affect DNA replication?

A) The effect would be negligible because uracil is found in RNA not DNA

B) The effect would be minimal because UTP if formed from the emanation of CTP

C) Uracil could be synthesized by a salvage pathway and so the effect would be minimal

D) DNA synthesis depends on dCTP formed by nucleotide reductase of dUTP

E) DNA synthesis depends on the synthesis of a short strand of RNA primer, thus DNA synthesis would be negatively impacted.

Explanation / Answer

The correct answer is option (A).

Reason: DNA (deoxyribonuceic acid) replication is a process that produces two identical copies of parent (original) DNA. According to the standard base-pairing law, in double-stranded DNA, adenine binds with thymine, and guanine is bind with cytosine. Since, uracil is found only in RNA (ribonucleic acid), not in DNA, the affect of a mutation that reduced the formation of uracil would be negligible in DNA replication.

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