1) A female patient has had a lifelong battle with sever muscle weakness. When h
ID: 98998 • Letter: 1
Question
1) A female patient has had a lifelong battle with sever muscle weakness. When her doctor examines her genome, he saw the following. What type of chromosomal mutation does she have?
choose one of the answers below:
a) inversion
b) Nonreciprocal translocation
c) Reciprocal translocation
d) duplication
e) Robertsonian translocation
f) Deletion
2) After the doctor discusses his findings with his patient, she wants to know what the probability is of passing this on to her offspring. Determine what gametes she can produce, and whether those gametes would be viable or not when fertilized with the sperm of a male with normal chromosomes 14 and 21. Use the image in the previous problem, where A, B, and C represent each chromosome. Each answer choice below represents a possible gamete combination. (Select all that apply).
a) B,C = muscle weakness
b) A,C = normal
c) C = muscle weakness
d) A,B = normal
e) A,C = not viable
f) A = normal
g) C = not viable
h) B = not viable
i) A,B = muscle weakness
j) B = normal
k) A = muscle weakness
l) B,C = not viable
m) B,C = normal
n) C = normal
o) B = muscle weakness
p) A,B = not viable
q) A,C = muscle weakness
r) A = not viable
3) Which of the following mutations WILL NOT alter the AMOUNT of genetic information? (select all that apply)
Deletion
Nonreciprocal translocation
Tandem Duplication
Pericentric Inversion
Robertsonian translocation
Reciprocal translocation
Paracentric Inversion
Reverse Duplication
Deletion
Nonreciprocal translocation
Tandem Duplication
Pericentric Inversion
Robertsonian translocation
Reciprocal translocation
Paracentric Inversion
Reverse Duplication
223 22.1 21 D 21 11.2 P 112 112 11.2 2.1 223 q 2 14 22 dert14,21) 24.1 24.2 23 der(14,21) 13 12 11-m1 21 22 22 12 13 21 22 31 13 12 "ut 11 12 13 21 22 23 24 31-32 32Explanation / Answer
1. The answer is
e) Robertsonian translocation
3. The answers are
Pericentric Inversion
Reciprocal translocation
Paracentric Inversion
These three of the above wil not alter the AMOUNT of genetic information. In peri and para centric inversion, the chromosome segment in the same chromosome will be inverted and in raceprocal translation the chromosome material will exchange in the two chromosomes.
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