People(average body weights=70kg) have been living in an industrial area, where
ID: 994203 • Letter: P
Question
People(average body weights=70kg) have been living in an industrial area, where the concentration of particle matter is 150ug/m^3 on average but only 1% of PM10 are benzene, which is human carcinogen. Assume that the life time for those people is 70years and the average inhalation is 20 m^3/day. The potency factor for benzene through inhalation is 0.029 (mg/kg/day)^-1. What are chronic daily intakes for the particle matter and benzene? What is the incremental lifetime cancer risk of those residents? CDI PMI=42.9 mg/kg/day CDI Benzene= 0.0429 mg/kg/day Cancer risk=1.24x10^-3 (or 1.24 per 1000) What are the steps(in detail) to get the answer?
Explanation / Answer
As there are just 150ug/m3 and there is 1% of benzene, then 1.5ug/m3. As the daily intake is 20m3/day, the daily intake is 1.5ug/m3*20m3/day = 30ug/day. As it is needed to know the value after 70yr then we must apply
C(25550) = 0.03mg*exp(0.029*25550) = 1.85e320 mg of benzene for all their life.
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