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ezto.mheducation.com Home Community -Liferay- Web06 Campus - BI0204CO9 Microbiology w/L McGraw-Hill Education Campus Homework Assignment # 4 (Chp 14, 1 McGraw-Hill Connect | ebook Bio 204 DEV: Bio 204C09 SU17 Philip Prause Homework Assignment # 4 (chp 14, 15 & 16) instructions I help Question 2 (of 5) Save &Exit; Submit Save & Exit Submit valuc: 4.00 points Order the following choices to test your understanding of the mechanism of action of allergy shots Allergen specific lgG antibodies formed Pure allergen injected No mast cell degranulation occurs lgG binds to allergen before it can bind IgE References eBook & Resources Ranking Section: 16.02

Explanation / Answer

Mechanism of action of allergy shots:-

1. Pure allergen is injected.

2.Allergen specific IgG antibodies are formed.

3.IgG binds to allergen before it can bind to IgE.

4. No mast cell degranulation occurs.

This is a kind of immunotherapy given to patients who are Type 1 hypersensitive. In this repeated shots of allergen are given to patients (generally injected subcutaneously) ,to which a person is allergic. This is done to increase IgG production and reduce IgE production and thus prevent Ag induced cross-linking of of mast cells and basophills. Thus preventing mast cell degranulation (relaese of vasoactive amines like histamines) and it's effects- vasodilation and smooth muscle contraction.

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