Make sure response is ONE paragraph or less. We learned that neurotransmitters:

Question

Make sure response is ONE paragraph or less.

We learned that neurotransmitters:
- Are released from presynaptic terminals (in response to action potentials) into a synapse
- Bind to receptors on postsynaptic cells to produce their actions
- Are removed from the synaptic cleft to terminate their actions

The mechanisms of action of various medications and drugs are based on the presence of or clearance of various neurotransmitters within the synaptic cleft. Based on the processes of neurotransmitter release, re-uptake, and binding, describe 1) a mechanism that might contribute to potentiating a neurotransmitter’s synaptic effects and 2) a mechanism that might contribute to limiting a neurotransmitter’s synaptic effects. Provide example situations where each of these mechanisms might play a physiological role.

Explanation / Answer

The long term potentiation (LTP) and long term depression (LTD) can be initiated by activating N-methyl-d-aspartate(NMDA) type glutamate receptors.

It is now accepted that the modest increase in postsynaptic calcium triggers LTD and much larger increase in postsynaptic calcium triggers LTP.

Related Questions

Navigate

• Browse (All)
• Browse M
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.