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(a) Arrange the following enzyme activities in order that they first appear in t

ID: 100040 • Letter: #

Question

(a) Arrange the following enzyme activities in order that they first appear in the biosynthesis of stearoyl CoA in the cytosol of the liver cell. (A) Acetyl CoA Carboxylase 1. _________ (B) Acetyl CoA Transferase 2. ____________ (C) beta -hydroxyacyl ACP-dehydratase 3. __________ (D) beta -ketoacyl ACP reductase 4. _________ (E) beta -hydroxyacyl CoA-dehydratase 5._________ (F) beta -ketoacyl CoA reductase 6. __________ (G) Elongase 7. _______ (H) Enoyl ACP reductase 8. _____ (I) Enoyl-CoA reductase 9. __________ (J) Fatty Acyl CoA Synthetase 10. __________ (K) Malonyl CoA Transferase 11. _____________ (L) Thioesterase 12 ______________ (b) How many ATP equivalents and NADPHs are required to synthesize arachidate from cytostolic acetyl CoA?

Explanation / Answer

1 NADH = 2.5 ATP, so 9 x 2.5 = 22.5ATP

9 FADH2 = 9 x 1.5 = 13.5 ATP

22.5+13.5 = 36 ATP