You have four identical Isolated neurons which are capable of forming excitatory
ID: 100531 • Letter: Y
Question
You have four identical Isolated neurons which are capable of forming excitatory ACh synapses on both ends. You treat each of these neurons with a different drug. You then apply acetylcholine to the dendrites of each neuron, and test to see if that neuron is capable of EPSP formation, action potential production, and/or acetylcholine release. The results to your studies are given here: a) Which drug is probably a placebo? Explain. b) Give a plausible explanation what each of the three other drugs might do, giving cellular and/or chemical details. Will give a thumbs up if correct, thank you.Explanation / Answer
Ans-A- A placebo is a drug which have no therapeutic effect but used as a control to test other drugs. In this case drug no 2 have no effect but it can act as negative control so drug no 2 is a placebo.
Ans-B- the drug no 1 cause epsp to open ligand gated ion channel and flow of positive ions like Na+ and K+ out of axon. These opening and closing make action potential due to depolarization and repolarization.
In drug no 3 there only epsp open the ligand gated ion channel but action potential does not reached.
In drug no 4 the epsp and action potential reached and they make the cells to secrete acetylcholine.
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