Why are people who have poor DNA repair mechanisms at greater risk for cancer de

Question

Why are people who have poor DNA repair mechanisms at greater risk for cancer development? Select one: a. Their cancers are usually resistant to chemotherapy. b. They have sustained the initial "hit in all cells and tissues. c. Their somatic mutations are more likely to be permanent. d. They have greater exposure to environmental carcinogens. What is the best description of the genetic contribution to onset of autism? select one: a. Known causes of autism spectrum include copy number variants and chromosomal problems. b. Autism spectrum disorders have a much stronger environmental input than genetic input to expression of the phenotype c. Autism spectrum is caused by a single gene mutation in most but not all cases. d. exposure to a teratogen can be a cause of autism spectrum in many cases.

Explanation / Answer

1. ANS: C

Explanation: In any case if DNA is damaged, the cell can able to repair it. In poor DNA repair mechanism people the accumulation of errors result in early senescence, apoptosis, or cancer.

2. ANS: A.

Explanation: The onset of autism is traditionally described as occurring in one of two patterns. In one onset prototype, children show abnormalities in social and communicative development in the first year or so of life.

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