8. What reaction does glucose 6-phosphatase catalyze? Where is this enzyme locat

ID: 1029805 • Letter: 8

Question

8. What reaction does glucose 6-phosphatase catalyze? Where is this enzyme located?

9. How many NTPs are expended in producing PEP from pyruvate? How many NTPs does it require to generate one glucose molecule in gluconeogenesis?

10. What is the purpose of reciprocal regulation between glycolysis and gluconeogenesis? What are the key regulatory steps?

11. Be able to describe the importance of fructose 2,6-bisphosphate in reciprocal regulation.

12. What is a bifunctional enzyme? Describe the alternative regulation of the bifunctional enzyme PFK/Fructose 2,6-bisphosphatase.

13. Describe the role of the Cori cycle in recycling lactic acid and ensuring that muscle cells can produce ATP during exercise.

Ans 8:

The enzyme glucose 6-phosphatase is located in endoplasmic reticulum of the cell.

It catalyses the final step of the gluconeogenesis.

It hydrolyzes glucose -6-phosphate and produces glucose molecule and one phosphate.

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