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1148 Final 2018 abbreviated names. One is called ACC and the other is called ACP

ID: 1031506 • Letter: 1

Question

1148 Final 2018 abbreviated names. One is called ACC and the other is called ACP A) (3 pts) Which of the two (ACC or ACP) is an enzyme and which is just a protein that carries other B) (10 pts) ACC catalyzes the very first step that makes the molecule that becomes all the carbons in the fatty acid except the first two. It is made from acetyl CoA. Write the mechanism of what ACC does to acetyl CoA showing all cofactors, steps, and products. C) (7 pts) The adipose tissue is where lipids are stored. Interestingly, adipose tissue responds to hormones such as insulin, glucagon, and epinephrine that sense blood glucose levels. This is why a high sugar diet can still make you fat. Fill in ALL the boxes in the diagram below based on what you know about which hormones are released in which state and which organs have receptors for which Il Page 9

Explanation / Answer

a. Fatty acid synthesis is a complex biological process which involves several enzymes, fatty acid synthases and other proteins. Acetyl-CoA carboxylase (ACC) is an enzyme that catalyses iireversible carboxylation of acetyl-CoA to malonyl-CoA. It plays a key role in controlling fattyacid metabolism. Acetyl carrier protein (ACP) also plays an important role in fatty acid synthesis. But this is not an enzyme like ACC. It carries acyl intermediates during fatty acid synthesis.