Assume that an Ames test is performed on an unknown compound. Plate A receives d

Question

Assume that an Ames test is performed on an unknown compound. Plate A receives distilled water and rat liver enzymes. The compound under test is placed in plate B. Plate C receives the compound under test and rat liver enzymes. The next morning plate A has only one or two colonies, plate B has many colonies, and plate C has many colonies. The best interpretation is:
(explain answer)

A. rat liver enzymes are mutagenic
B. the compound being tested is mutagenic
C. only auxotrophic colonies can grow on the test plates
D. the compound being tested is not mutagenic, but can be converted to mutagenic compounds by the rat liver enzymes
E. the compound being tested is mutagenic but the rat liver enzymes destroyed the mutagens

Explanation / Answer

Assume that an Ames test is performed on an unknown compound. Plate A receives distilled water and rat liver enzymes. The compound under test is placed in plate B. Plate C receives the compound under test and rat liver enzymes. The next morning plate A has only one or two colonies, plate B has many colonies, and plate C has many colonies. The best interpretation is:


A. rat liver enzymes are mutagenic
B. the compound being tested is mutagenic
C. only auxotrophic colonies can grow on the test plates
D. the compound being tested is not mutagenic, but can be converted to mutagenic compounds by the rat liver enzymes
E. the compound being tested is mutagenic but the rat liver enzymes destroyed the mutagens

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