Human albinos have no pigmentation in their skin, hair, or irises of the eyes. S
ID: 11955 • Letter: H
Question
Human albinos have no pigmentation in their skin, hair, or irises of the eyes.Suppose that you gathered hospital records for the past 50 years for
normally pigmented couples who gave birth to one or more albino children. You
find that there were 70 normally pigmented babies and 17 albino babies born to
these couples. Use a chi-square test to determine if this pattern is a good fit to a
3:1 ratio (pigmented:albino), and explain your reasoning. (8 points) (You don't
have to show all of your calculations – just give the chi-square and P values, then
explain.)
Explanation / Answer
albinos have no pigmentation in their skin,-recessive tr ait ---------------a
normal ------------A
Aa xAa
A
a
A
AA normal
Aa normal
a
aA normal
aa albinos
Ratio- 3:1
As every issue is independent event
Mendel’ law---------3:1------------law of dominance
chi-square test
Observed
expected
o-e
(o-e)^2
(o-e)^2/E
normal
70
65
5
25/65
0.38
albinos
17
22
-5
25/22
1.13
Total
87
87
1.51
chi-square test –VALUE----------1.51, IS LESS THAN TABLE VALUE AT 5% LEVEL OF SIGNIFICANCE
SO fit to a3:1 ratio
A
a
A
AA normal
Aa normal
a
aA normal
aa albinos
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