Surgery was performed as usual with UFH. Neither UFH nor any low molecular weigh
ID: 121962 • Letter: S
Question
Surgery was performed as usual with UFH. Neither UFH nor any low molecular weight heparin was given in the immediate post-operative period. The effects of UFH and enoxaparin were monitored by the activated partial thromboplastin time (aPTT) and the Enox-test (sensitive to factor Xa inhibition) using a Rapidpoint Coagulation Analyzer. aPTT and factor Xa activity were also measured by standard methods. Peri-operative bleeding and the nadirs of hemoglobin concentration, hematocrit and platelet count were monitored post-operatively.
Pre-operative bridging therapy(UFH or LMWH) after the period that interruption of some anticoagulation, the drug which are mostly used for this administration?
Explanation / Answer
The American College of Chest Physicians proposed guidelines for antithrombotic prophylaxis in patients with different risk factors. While performing the non-cardiac surgeries the main concern is safe to perform surgery without increasing the risk of hemorrhage and thromboembolism. So after interruption anticoagulation drugs like Warfarin, Dabigatran, Rivaroxaban, Apixaban, and Endoxaban are generally administrated to the patients.
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