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Endocrine Case study A 48 year old woman with a past history of mental illness p

ID: 125614 • Letter: E

Question

Endocrine Case study

A 48 year old woman with a past history of mental illness presented with a new onset of bizarre psychotic behavior. She had been well for the past two years.

Upon physical exam, she was 5'5" tall and weighed 138 lb. Her heart rate was 80 and her blood pressure was 130/75. The physical exam was otherwise normal except that she was confused as to the current location, the date, and the year.

Initial laboratory tests revealed:

A blood sample was sent for parathyroid (PTH) analysis. In the meantime, the patient and her family were questioned further. There was no history of bone pain, recent fractures, or kidney stones. The patient did not use diuretics. A breast exam, mammography, and chest X Ray did not suggest malignancy. Stool analysis for occult blood was negative.

The parathyroid hormone tests yielded the following results:


Exploratory surgery of the neck yielded a large solitary parathyroid adenoma. Calcium levels declined postoperatively and the psychotic symptoms subsided. The patient was discharged on the 5th postoperative day.

*Please help identify the condition (This is all of the information that I was provided)

Patient Reference Range Sodium 143 136-145 mEq/L Potassium 3.4 3.5-5.1 mEq/L Chloride 104 98-107 mEq/L CO2 28 22-28 mEq/L Glucose 135 74-100 mg/dL BUN 10 6-20 mg/dL Creatinine 1.1 0.9-1.3 mg/dL Calcium 13.8 8.6-10.2 mg/dL Total Protein 6.9 6.4-8.3 g/dL Albumin 4.2 3.5-5.2 g/dL Total bilirubin 0.5 0-2.0 mg/dL ALP 56 53-128 U/L AST 36 <35 U/L ALT 18 <45 U/L

Explanation / Answer

Earlier the patietn has hypercalcemia.

The PTH test measures the level of parathyroid hormone in the blood. PTH stands for parathyroid hormone. It is a protein hormone released by the parathyroid gland. A laboratory test can be done to measure the amount of PTH in your blood.

When the calcium in our blood goes too low, the parathyroid glands make morePTH. Increased PTH causes the body to put more calcium into the blood.Increased PTH causes the bones to release their calcium into the blood.

The above lab results have the above mentioned relation.

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