Your 59-year old male pateint is in the clinic today reporting that he thinks so

Question

Your 59-year old male pateint is in the clinic today reporting that he thinks something is wrong with his week old ileostomy. He also reports burning during urination. Before the nurse practioner sees the pateint, you reveiw his medications. He does not have a list of medications, so you review his chart and then review his medications with him.

Home Medications:

Atropine .3 my every 4-6 hours as needed

Chlordiazpoxide(Librium) 5 mg every 8 hours

Cholestyramine (Questran) 4 mg every morning

Desvenlafaxine (Pristiq) 50 mg 1 tab every morning

Ibuprofen (Motrin) 800 mg as needed for pain

Potassium Chloride 10 mEq 1 tab every morning

Sildenafil (Viagara) 25 mg 1 hour prior before sexual activity

Does the indivuals medical history have an effect on the pharmokinetics of each drug??

Explanation / Answer

The individual’s medical history will have an effect on the pharmacokinetics of each drug as Pharmacokinetics involves determining the fate of substances administered to a living organism. Hence the medical history i.e. the

Age
Circulation
Nutrition
Hydration / urine elimination
Water and/or fat solubility of drug
Enzyme inducers
Body fat

Will control the fate i.e. half-life of the drug.

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