100 80 60 40 20 ? Control DNP 20 40 60 80 100 120 4 Age (weeks) Source: c. C. Ca

Question

100 80 60 40 20 ? Control DNP 20 40 60 80 100 120 4 Age (weeks) Source: c. C. Caldelra da Stva eal. 2008 Agvig Cev 7:552 D560. hese included increased respiration ?nd even death Propose an explanation In he 1930s. DNP was introduced as der drug until i was banned rom human use because o adverse side effects when h gh concentrations o the drug were used for the sicde ettects based on the ettect DNP has on the proton gradient Drag the terms on the left to the appropriate blanks on the right to complete the sentences Reset Help The increased respiration likely anises trom an elevated demand for clectron transport to addrcss the ATP to drive reduced elriciency of citrate synthcsis. Death is likcly duo to insuticient NAD+ being produced lo keep cells alie increased

Explanation / Answer

Answer. 2,4-dinitrophenol or DNP acts as a potent protonophore that allows protons to leak from the inner Mitochondrial membrane surpassing ATP synthase. Thus, ATP production becomes quite less, and major amount is wasted as heat.

The increased respiration likely arises from an elevated demand for oxygen to drive ET to address the reduced efficiency of ATP synthesis. Death is likely due to insufficient NAD+....

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