Based on antigenic differences in H chains, antibodies have been divided into th
ID: 132453 • Letter: B
Question
Based on antigenic differences in H chains, antibodies have been divided into the following classes: a) IgG and IgA b) IgM and IgD c) IgE d) All of the above 12) None of the above 13) Quantitatively the largest class of immunoglobulins in human serum is: b) Ig c) IgM d) IgD e) Ig 4) Which of the following statements are applicable to IgM immunoglobulins: a) They are the antibodies first to be detected after injection of an antigen b) In the presence of complement, they are highly lethal to gram-negative bacteria c) They play an impo9rtant protective role during the early stags of infection d) All of the above None of the above Hypersensitivity in due to: . The presence of an antigen. b. Immunity e. The presence of antibodies. d. An altered immune response. e. Allergies. 16) Dasensitization to prevent an allergie response can be accomplished by injeeting small, repented doses of . IgE antibodies b. The antigen (allergen). e. Histamine d. IgG antibodies. e. Antihistamine.Explanation / Answer
12. Antibodies comprise of basic structure with four peptide chains. Two identical heavy (H) chains and two light (L) chains. Heavy and light chains further have constant (C) and variable (V) regions.
Thus:
Light chain domains- VL and CL.
Heavy chain domains- VH and CH
Due to antigenic variation in H chain (Constant region), antibodies are subdivided into 5 classes:
Answer. d.
13. Immunoglobulin G (IgG) are most prevalent Ig in serum ad extravascular spaces. Quantitively they are more abundant than other antibodies.
Answer: A
14.
Answer: d.
15. Hypersensitivity may be defined as an exaggerated or excess (hyper) immune response towards an antigen, due to a state of altered immunity in the body. Hypersensitivity may be classified into class I, II, III, IV. Type I hypersensitivity is referred to as allergic reactions or allergies.
Answer: d.
16. Desensitization or hypo-sensitization is a process of allergen immunotherapy for treating some allergies. In this technique, the patient is injected with small doses of antigen or allergen, to elucidate an immunogenic memory or immune cell generation.
Answer:b.
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