Gene homologues. Back at the top of the http://www.ncbi.nlm.nih.gov/ page, under
ID: 132699 • Letter: G
Question
Gene homologues. Back at the top of the http://www.ncbi.nlm.nih.gov/ page, under the ‘All databases’ tab select the ‘Homologene’ database and enter your gene of interest into the search tab which is(CTNNA1) alpha-catenin) .
How many homologues to your human gene are listed with this tool?
two.
Over what classification level has your gene been conserved? for ex., the gene KRT5 has been conserved since the evolution of tetrapods.
One was conserved in Bilateria , and the other in Tetrapoda
Does your answer to the above question suggest your gene is an ‘ancient’ gene or a more recent addition in our evolutionary history? Give an estimate, in millions of years, when the gene diverged in our ‘common ancestor’ with other species…
What are a few of the more obscure species where your gene has been identified?
Give your impression on the number of amino acids in the protein product of your gene across the different organisms listed. What does this pattern suggest?
.
How many homologues to your human gene are listed with this tool?
Over what classification level has your gene been conserved? for ex., the gene KRT5 has been conserved since the evolution of tetrapods.
Does your answer to the above question suggest your gene is an ‘ancient’ gene or a more recent addition in our evolutionary history? Give an estimate, in millions of years, when the gene diverged in our ‘common ancestor’ with other species…
What are a few of the more obscure species where your gene has been identified?
Give your impression on the number of amino acids in the protein product of your gene across the different organisms listed. What does this pattern suggest?
Explanation / Answer
Please find the answers below:
Answer 1: Based upon the information in the output tool, only two homologues of this gene are available, one conserved in bilateria and other conserved in tetrapods.
Answer 2: Based upon the information, it can be deduced that the most primitive form of this gene has been conserved since the origin and survival of the bilateria.
Answer 3: Yes, the information undoubtedly states that the gene is very ancient in nature. In fact, since the bilateria are more than 500 millions year old in origin, so is the age of this gene.
Answer 4: Some of the most unique species where this gene can be found include Homo sapiens, C. elegans, D. rerio, Gallus gallus etc. This suggests the wide distribution of the gene throughout the animal kingdom.
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