link to model: https://media.pearsoncmg.com/bc/bc_0media_gen/jsmol/t7dnapol/t7dn
ID: 135555 • Letter: L
Question
link to model: https://media.pearsoncmg.com/bc/bc_0media_gen/jsmol/t7dnapol/t7dnapol.html
Part B
In which domain is the bottom of the DNA-binding cleft? What type of secondary structure lines the bottom of the cleft?
a. The bottom of the cleft is in the thumb domain. It is lined with both alpha helices and a beta sheet. b. The bottom of the cleft is in the fingers domain. It is lined with alpha helices. c. The bottom of the cleft is in the fingers domain. It is lined with a beta sheet. d. The bottom of the cleft is in the palm domain. It is lined with a beta sheet. e. The bottom of the cleft is in the palm domain. It is lined with alpha helices.Explanation / Answer
The answer is d) The bottom of the cleft is in the palm domain. It is lined with a beta sheet.
Well, to understand this just imagine the structure of the polymerase as open right hand. So this is then divided into three parts namely - fingers, palm and thumb. Here thumb and fingers form a cleft such that palm is present as a plate at the bottom of this cleft. And the DNA is present in the palm domain.
Mostly polymerase consists of alpha helices but palm domain consits of beta sheets.
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