What would occur to gene expression if all of the chromatin remodeling complexes

Question

What would occur to gene expression if all of the chromatin remodeling complexes were removed from the cell?

Question 9 options:

All genes would be expressed constantly

Gene expression regulation would be reduced; some proteins would be expressed more and some would be expressed less

The structure of mitotic chromosomes would become very loose

All gene expression would stop

All genes would be expressed constantly

Gene expression regulation would be reduced; some proteins would be expressed more and some would be expressed less

The structure of mitotic chromosomes would become very loose

All gene expression would stop

Explanation / Answer

Option 1 is the correct answer.

Chromatin remodelling refers to the rearrangement of chromatin from a condensed state to a transcriptionally accessible state, allowing transcription factors or other DNA binding proteins to access DNA and control gene expression. Thus, chromatin remodelling allows for the "Controlled access" of the genes by the transcription factors, meaning that for a gene expression to take place, chromatin must allow access to that gene by means of remodelling. Now, suppose if all the remodelling complexes have been removed, in such a case, the genes will laways be open, i.e., they would be constantly accessible by the various transcription factors or proteins required for the expression of gene. As such, the genes will be expressed constantly in the absence of chromatin remodelling complexes.

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