Compare and contrast the enolase reaction in glycolysis with the fumarase reacti
ID: 142901 • Letter: C
Question
Compare and contrast the enolase reaction in glycolysis with the fumarase reaction in the TCA cycle. What kinds of reactions are involved (what is happening)? What do the reactions have in common, and/or what is different? Write out the chemical reactions (without mechanisms) and explain. Compare and contrast the enolase reaction in glycolysis with the fumarase reaction in the TCA cycle. What kinds of reactions are involved (what is happening)? What do the reactions have in common, and/or what is different? Write out the chemical reactions (without mechanisms) and explain.Explanation / Answer
Enolase in glycolysis catalyzes the conversion of 2-phosphoglycerate to phosphoenol pyruvate in glycolysis. Enolase catalyzes this reaction by removing a water molecule from 2-phospho glycerate.
Thus, the conversion of 2-phospho glycerate to phosphoenol pyruvate is a reversible dehydration reaction.
2-Phospho glycerate <-----------> phospho enol pyruvate + H2O.
The enzyme fumarase catalyzes the conversion of fumarate to malate in TCA cycle.
Conversion of fumarate to malate is reversible hydration reaction.
Fumarate<------------->malate
The similarity in both of the above reactions is their reversible nature.
The difference in both of them is Enolase reaction is dehydration reaction and fumarase reaction is hydration reaction.
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