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1) explain why orgigins of replication along a chromosome tend to start at sites

ID: 143746 • Letter: 1

Question

1) explain why orgigins of replication along a chromosome tend to start at sites with stretches of A and T nucleotides. 2) if nucleotides in a strand of DNA have single phosphate groups linking them, why does DNA polymerase III use deoxynucleoside triphosphate molecules as the precursor molecules? 3) Explain the problem posed by the moving replication forks of a replicon in terms of how DNA pol III fictions. Question 1 (2 pts): Explain why origins of replication along a chromosome tend to start at sites with stretches of A and T nucleotides. Question 2 (2 pts): If nucleotides in a strand of DNA have single phosphate groups linking them, why does DNA Polymerase III use deoxynucleoside triphosphate molecules as the precursor molecules? Question 3 (2 pts): Explain the problem posed by the moving replication forks of a replicon in terms of how DNA Pol III functions. Question 4 (10 pts): Draw in the newly synthesized DNA within the replicon below. . Draw arrows at ends of strands to indicate the direction of their synthesis. Label: Leading strand, Lagging strand, Okazaki fragments, RNA primers 3' 5' 5 3'

Explanation / Answer

Replication start at stretch site of A and T nucleotides because adenine and thymine easier to separate because there base stacking interaction are not strong as guanine and cytocine...