The figure above shows the action of NGF on rat sensory neurons. Action potentia
ID: 145425 • Letter: T
Question
The figure above shows the action of NGF on rat sensory neurons. Action potentials (APs) were elicited by stimulating the sensory neurons. The control bar (Cont) shows the average number of action potentials (APs) elicited after stimulation of untreated neurons. Separate preparations of neurons were treated with NGF, as indicated, before being stimulated and the number of action potentials was counted.
What does the data above show?
Treatment of neurons with 6-20 µM with NGF before stimulation maximally increased the number of action potentials compared to untreated neurons.
After 6 minutes of NGF treatment, by how much had the number of APs increased?
four times
How could this data be interpreted?
1) Treatment of 6-20 neurons with NGF maximally increased action potentials. 12 Untreated Cont Untreated +NGF Cont 2 6 10 20 NGF (min)Explanation / Answer
=> 2) Treatment of neurons for 6-20 minutes with NGF before stimulation maximally increased the number of action potentials compared to untreated neurons. The graph clearly shows the NGF treated upto 20 minutes, and the concentration of NGF is not mentioned.
=> 1) 2.5-fold. Number of APs has been increased from 3 (as in untreated control) to 8 (NGF, 6 min). Therefore 8/3 = 2.667 times increase.
=> 2) NGF increases the number of action potentials of sensory neurons after stimulation. Number of action potential increase from 3 (in untreated control) to 9 in 10 minutes.
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.