True/False: The antibody protein has two functional domains, one variable domain

Question

True/False:The antibody protein has two functional domains, one variable domain for antigen binding and a second, constant domain to confer specific effector functions. These two functional domains are encoded by the antibody light chain and antibody heavy chain polypeptides, respectively. (1)

True/False: MHC class I molecules generally bind peptides that are 8–10 amino acids. Each allelic variant has preferences for the amino acid residues at key anchor positions, but will not bind every possible peptide containing the correct anchor residues. (1)

Explanation / Answer

1) The antibody protein has two functional domains, one variable domain for antigen binding and a second, constant domain to confer specific effector functions. These two functional domains are encoded by the antibody light chain and antibody heavy chain polypeptides, respectively.

This is FALSE because Variable and constant regions are present on both Heavy and Light chain. One does not contain each.

2) MHC class I molecules generally bind peptides that are 8–10 amino acids. Each allelic variant has preferences for the amino acid residues at key anchor positions, but will not bind every possible peptide containing the correct anchor residues.

I think this should be TRUE, i am sure about 8-10 amino acid peptide binding to MHC but not so sure about possible anchor sequences.

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