QUESTION 1 A patient presents with metabolic alkalosis (blood pH above normal le

Question

QUESTION 1 A patient presents with metabolic alkalosis (blood pH above normal levels) as a result of excessive vomiting due to food poisoning. Which of these curves represents Hb oxygen-binding under alkalosis conditions? 100 w 90 80 70 50 30 20 10 0 10 20 30 40 50 60 70 80 90 100 110 120 Oxygen partial pressue (mg) Curve A Curve B QUESTION 2 BPG (2.3-bisphosphoglycerate) lowers Hemoglobin's (Hb) affinity for oxygen by: Disrupting the interactions between the a and ß subunits of Hb. Binding to oxygen molecules Stabilizing the Tense conformation of Hb. ODirectly binding to the heme group Fel(l) atom.

Explanation / Answer

1. Curve A. In alkalosis, in oxygen curve shifts to left.

2. BPG disrupts the interaction between alpha and beta subunits of hb.

4. Km represents total concentration in a reaction.

5. Enzymes make reaction more exergonic is false.

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