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The energy for protein synthesis comes from which of the following? The ATP used

ID: 162396 • Letter: T

Question

The energy for protein synthesis comes from which of the following?

The ATP used in the synthesis of aminoacyl-AMP molecules that are then converted to aminoacyl-tRNAs

The GTP that is bound to initiation factors used in the initiation and translocation phases of translation

The high energy C-N bond of the amino acid

a, b, and c

a and b

The enzymatic process of "charging" a molecule of tRNA is similar to other enzyme catalyzed reactions. Which of the following correctly describes such similarities?

Formation of an acyl-adenylate intermediate coupled to the hydrolysis of pyrophosphate in fatty acid activation is similar to reactions involved in the "charging" of tRNA.

Proofreading and correcting abilities that prevent incorporation of the wrong molecule are analogous to the action of DNA polymerase.

The aminoacyl-tRNA synthetase is a relatively non-specific enzyme (i.e., it can activate many different amino acids) and, in this respect, is similar to ribonucleotide reductase.

a and b.

e.

b and c.   

a.

The ATP used in the synthesis of aminoacyl-AMP molecules that are then converted to aminoacyl-tRNAs

b.

The GTP that is bound to initiation factors used in the initiation and translocation phases of translation

c.

The high energy C-N bond of the amino acid

d.

a, b, and c

e.

a and b

Explanation / Answer

1. The answer is: e. a and b

The energy for protein synthesis comes from :

i. The ATP used in the synthesis of aminoacyl-AMP molecules that are then converted to aminoacyl-tRNAs

ii. The GTP that is bound to initiation factors used in the initiation and translocation phases of translation

2. The answer is: d. a and b.

The correct similarities are:

i. Formation of an acyl-adenylate intermediate coupled to the hydrolysis of pyrophosphate in fatty acid activation is similar to reactions involved in the "charging" of tRNA.

ii. Proofreading and correcting abilities that prevent incorporation of the wrong molecule are analogous to the action of DNA polymerase.

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