Calculate the energetic cost of nucleoside triphosphates consumed during one rou

Question

Calculate the energetic cost of nucleoside triphosphates consumed during one round of elongation after initiation is completed. Describe how the nucleoside triphosphate is used.

Drag the phrases on the left to the appropriate blanks on the right to complete the sentences.

__________ hydrolyzed during tRNA charging. This energy is stored in the acyl bond for peptide bond formation. __________ hydrolyzed when EF-Tu dissociates from the ribosome after the correct codon/anticodon base pairing occurs between the codon and tRNA in the A site. __________ hydrolyzed during translocation. Hydrolysis of the __________ coupled to maintaining the order of the events of elongation and the specificity of that event (for EF-Tu).

One GTP (carried by EF-G) is

One ATP is

One GTP is

Two GTP molecules is

Explanation / Answer

For elongation one round - 2 GTP will be used because amino acid has already been activated and no further energy will be required for a peptide bond formation.

ATP hydrolyzed during tRNA charging. This energy is stored in the acyl bond for peptide bond formation. One GTP hydrolyzed when EF-Tu dissociates from the ribosome after the correct codon/anticodon base pairing occurs between the codon and tRNA in the A site. One GTP( carried by EF-G ) hydrolyzed during translocation. Hydrolysis of the two GTP molecules is coupled to maintaining the order of the events of elongation and the specificity of that event (for EF-Tu).

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