The chemical brefeldin A is a naturally occurring compound made in fungi that in

Question

The chemical brefeldin A is a naturally occurring compound made in fungi that inhibits the association of COPI coat proteins with membranes specifically in the cis Golgi.

For each of the following, determine if and how the process described would be affected by the addition of brefeldin A to the cells.

a. Retrograde transport of proteins containing a KDEL ER retention signal

b. Anterograde transport of proteins that will eventually be secreted from the cell by regulated exocytosis.

c. Modificiation of a glycosyl group on a protein by an enzyme that is only present in the trans Golgi.

Explanation / Answer

Answer would be .... A) retrograde transport of proteins containing a KDEL ER retention signal .

Memory based hope it helps ..... Regard

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