Aquaporins are integral membrane proteins that, perhaps obviously, form pores in

Question

Aquaporins are integral membrane proteins that, perhaps obviously, form pores in the membranes of biological cells. Some aquaporins are heterotetrameric in the active form. Solving the xray structure of an intact, active heterotetramer requires heroic efforts in crystallization, oftentimes unachievable. If the xray structures of the four individual monomers are known, using neutron scattering, how could you verify that the determined structures are the same as when in the intact letramer, and if they are, determine the structure of the heterotetramer?

Explanation / Answer

Aquaporin are small molecules channel found in several organism Structure was determined according to it there are two tetramers in the unit. cell composed of four copies of promoter A as tetramer and four of promoter B respectively. Positioning of these two tetramer show quasi14 symmetry.

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