We have considered several different kinds of cell-cell junctions found in epith

Question

We have considered several different kinds of cell-cell junctions found in epithelial cells. For the two types here, desmosomes and hemidesmosomes, select the correct properties or functions associated with it: (A)Signaling: recruits signaling molecules to its cytoplasmic side that convey information to the cell about its surroundings. (B) Shape and mechanical strength: contributor to the resistance of the whole epithelial sheet to stretching and tearing, and/or to its ability to change shape. (C) Brings the plasma membrane of adjacent cells into such close apposition that even small molecules can't leak between the cells. (D) Interacts with intermediate filaments at their cytoplasmic sides (E) Allows epithelia to maintain solute gradients between their apical and basal sides. (F) contains transmembrane proteins of the integrin family (G) Interacts with actin filaments on their cytoplasmic sides (H)Major source of adhesion between cells (I)Keeps the sheet anchored: mediates interaction of the cells with the basal lamina, or underlying extracellular matrix. (J) contains transmembrane proteins of the cadherin family

Explanation / Answer

Answer) Correctly labeled properties of these junction molecules is given below;

i) Desmosomes-D, H, J

ii) Hemi-desmosomes- A, D, I, F

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