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We have considered several different kinds of cell-cell junctions found in epith

ID: 71641 • Letter: W

Question

We have considered several different kinds of cell-cell junctions found in epithelial cells. For the two types here, tight and adherens junctions, select the correct properties or functions associated with it:

tight junctions:

adherens junctions:

Choices:

(A) Keeps the sheet anchored: mediates interaction of the cells with the basal lamina, or underlying extracellular matrix.
(B) Major source of adhesion between cells
(C) Shape and mechanical strength: contributor to the resistance of the whole epithelial sheet to stretching and tearing, and/or to its ability to change shape.
(D) Brings the plasma membrane of adjacent cells into such close apposition that even small molecules can’t leak between the cells.
(E) Interacts with actin filaments on their cytoplasmic sides
(F) Interacts with intermediate filaments at their cytoplasmic sides
(G) contains transmembrane proteins of the integrin family
(H) Allows epithelia to maintain solute gradients between their apical and basal sides.
(I) Signaling: recruits signaling molecules to its cytoplasmic side that convey information to the cell about its surroundings.
(J) contains transmembrane proteins of the cadherin family

Explanation / Answer

F) is associated with desmosomes.

(I) is associated with gap junctions.

Tight junction A,D,H Adheren junction B,C,E,G,J
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