How many cases of HSV infections are expected per year in a population of 1 000

Question

How many cases of HSV infections are expected per year in a population of 1 000 000 people of which 20% are either smokers or E-cigarette users?

Consider the following information and data to answer the questions that follow A study was done to investigate the occurrence of cold sores, caused by HSV, among cigarette smokers as compared to E-cigarette users. The study was performed over a 4 year period among 1000 cigarette smokers and 2000 E-cigarette users. At the beginning of the study each individual was screened to verify the presence of latent HSV, an incurable infection. Total cases Year of E-cigarette study Cigarette 20 30 2 105 40

Explanation / Answer

Q8: The transmissibility of HSV over the four year period expressed per 1 000 people is:
Cigarette:
= 20+40+45+100
= 205
The transmissibility of HSV over the four year period expressed per 2 000 people is:
ECigarette:
=30+ 105+140+210
=485
Hence the transmissibility of HSV over the four year period expressed per 1 000 people is:
= 2000/2 =1000
485/2
= 242.5
The number of smokers or E-cigarette in a population of 1 000 000 people of which 20% are either smokers or E-cigarette users is
20% of 1 000 000
20/100 x 1 000 000
0.2 x 1 000 000
200000 are either smokers or E-cigarette users
= 200000/1000
= 200 thousand
The average transmissibility of HSV over the four year period expressed per
1 000 people is:
Cigarette + ECigarette (transmissibility of HSV) :
= 205 + 242.5/2
=447.5
= 223.75
Since there are some 200 thousand
= 223.75 x 200
= 44750 cases

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