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When a small number of individuals moved to the United States from Germany, they

ID: 176083 • Letter: W

Question

When a small number of individuals moved to the United States from Germany, they established an Amish population. Why do you often see a higher prevalence of some rare diseases in these new founder populations?

a) Higher mutation rate in the new population. b) Alleles that are rare in the ancestral population (Germany) become common in the new population by random chance. c)Natural selection favors disease causing mutations in the new population. d)Negative assortative mating in the new population.

Explanation / Answer

Answer: B

When a small population is settled from a large population it experience founder effect i.e there is loss of genetic diversity. Certain allele may be lost and some rare allele may become common in future generation. So answer is B

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