Anther and Black loci are very closely linked on chromosome|(such that recombina

Question

Anther and Black loci are very closely linked on chromosome|(such that recombination can ignored-i.e there is essentially on recombination between these loci) Color is on chromosomal, and Deadly is on chromosome III. A close is has small anthers and albino petals that are non-toxic. From previous crosses you also known that Line 2 is homozygous set up between two true-breeding lines non-toxic, From F_2 generation has small anthers and albino petals that are cross are then salted to produce an Explain. recessive at the Black locus. The and light purple petals are non-toxic probability of getting a plant in the F, that has big anthers What is the most likely mode of inheritance of the trait (filled symbols) in the pedigree? Assume that the trait is 100% penetrate and is very rare in the population at large (i e individuals II-2 ll 4, and II-7 are very unlikely to be carriers). Explain your answer Because you love genetics so much, you have decided to become a genetics counselor You set up shop, and Because you love your first clients, Alfred and Alexi, come into your office. They want to start a family Through your questions, observations tests, you find out the following: Alexi previously had a son by another man. The boy died of a genetic disease that is 100% penetrate and displays a very early onset Alfred's sister died of the same disease. The disease is population at large. Nobody else in the family has the disease. What is the probability that Alfred and Alexi produce a child with the disease? Explain.

Explanation / Answer

5. from the pedigree, it is found that the disease or trait was spread almost half of the offsprings from the affected parents. However, the disease is not sex-linked as if the trait is X-linked then the sons would not be affected. The trait is therefore, autosomal dominant as the trait is appeared in every generation. However, it is found that the offsprings of II-3 are not affected, and they skip the trait. It resembles that II-4 is not the carrier of the trait and so as II-2. However, II-7 and II-8 have 1/2 of the affected children and that must came from their mother.

6. Alexa had a boy with a genetic disease and Alfred's sister had the same disease. Therefore, Alfred's may the carrier of the disease. Alexa may be the carrier or may be not because the disease phenotype may come from her husband. So, in this case, with the chance of carrier, Alfred has a chance to produce a disease child is 1/2 and Alexa has also a chance to produce a disease chiild is 1/2, if consider she is the carrier. Then the probability of having a disease child is = 1/2 x 1/2 =1/4.

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