Construct the sequence of events leading from a dietary vitamin C deficiency to

ID: 176240 • Letter: C

Question

Construct the sequence of events leading from a dietary vitamin C deficiency to symptoms such as bruising and breakdown of supporting tissues.

Rank the events from the first to the last.

collagen breaks down

enzyme prolyl hydroxylase is inactive

the triple helix is inadequately stabilized

defects in tissues that depend on collagen

proline is not hydroxylated

tissue levels of ascorbic acid is low

tissues that depend on collagen are subject to breakdown and bruise.

First Last

The sequence of events from the first to the last in the dficiency of Vit-C:

1. Tissue levels of ascorbic acid is low

2. Enzyme prolyl hydroxylase is inactive

3. Proline is not hydroxylated

4. The triple helix is inadequately stabilized

5. Collagen breaks down

6. Defects in tissues that depend on collagen

7. Tissues that depend on collagen are subject to breakdown and bruise.

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