Progression through the cell cycle requires a cyclin to bind to a Cdk because. t
ID: 176687 • Letter: P
Question
Progression through the cell cycle requires a cyclin to bind to a Cdk because. the cyclins are the molecules with the enzymatic activity in the complex. the binding of a cyclin to Cdk is required for Cdk enzymatic activity. cyclin binding inhibits Cdk activity until the appropriate time in the cell cycle. without cyclin binding, a cell-cycle checkpoint will be activated. Which CDK is most active during S phase? CDK1 CDK2 CDK4 CDK6 Mitogens are. extracellular signals that stimulate cell division. transcription factors important for cyclin production. kinases that cause cells to grow in size. produced by mitotic cells to keep nearby neighboring cells from dividing. The Retinoblastoma (Rb) protein blocks cells from entering the cell cycle by. phosphorylating Cdks. marking cyclins for destruction by proteolysis. inhibiting transcription of proteins needed for cell proliferation. promoting cell death (apoptosis). DNA damage usually causes cells to stop dividing and arrest at a G_1 checkpoint to promote production of p21 activation of p27 inactivation of p53 inactivation of Rb the G_1 DNA damage checkpoint. causes cells to proceed through S phase more quickly. involves the degradation of p53. is activated by errors caused during DNA replication. involves the inhibition of cyclin-Cdk complexes by p21. Cells in the G_0 state. do not divide. cannot re-enter the cell cycle. have entered this arrest state from either G_1 or G_2. have duplicated their DNA.Explanation / Answer
6. b. The binding of cyclin to cdk is required for cdk enzyme activity.
7.b CDK 2.
8.a .mitogens are extra cellular substances that stimulate cell division.
9.c.Inhibiting transcription of proteins needed for cell proliferation.
10 c.Inactivation of p53.
11. c.is activated by errors caused during the DNA replication.
12.c. Have entered this arrest state from either G1 or G2
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