31. Which of the following a dicer. A. It is part of the microprocessor complex

Question

31. Which of the following a dicer.
A. It is part of the microprocessor complex containing pasha or DGCR8
B. It has Argonauts family of protein
C. It has a piwi protein as a partner.
D. It has RNAse III domains and a PAZ domain

32. Why drosha is necessary for processing miRNA but not for processing siRNA?
A. Drosha cuts dsRNA in a sequence-specific manner
B. Drosha cuts dsRNA in by recognizing structure of the dsRNA
C. Dicer is for processing siRNA, drosha is for processing miRNA
D. The siRNA substrate lacks any secondary structure

Explanation / Answer

32.

C. Dicer is for processing siRNA, drosha is for processing miRNA.

The microRNAs generated are short RNA molecules that regulate a wide variety of other genes by interacting with the RNA-induced silencing complex (RISC) to induce cleavage of complementary messenger RNA (mRNA) as part of the RNA interference pathway.

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