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Now that you have concluded the target system, it is important for you to know t

ID: 178965 • Letter: N

Question

Now that you have concluded the target system, it is important for you to know that the neurologic examinations revealed that the most severely ill worker had ocular muscle weakness and was unable to maintain an upward gaze. In addition, this person had decreased sensation to light touch below the left knee. Otherwise, all other neurologic findings were unremarkable. Results of plasma and red blood cell cholinesterase activity tests were within the normal range for all workers tested. What agent or agents do you feel may be the culprits in this case? If you are still unsure about the agent causing the problem, here is your final clue. Your investigation and questioning has found that there are 22 different preparations of insecticide dips, shampoos, pills, powders, and sprays used in the clinic or dispensed by the clinic These products include 12 types of pesticides. Employees use no precautions to protect the skin. How might you secure information regarding the operation at the clinic with sick workers and other pesticide usage by other veterinary clinics

Explanation / Answer

Ques-3:

The pesticide, fenthion is the responsible agent for these effects in the seriously ill worker because, it has minor acute effects in humans and mammals & induce acute toxicity of muscle weakness. Other side effects are decreased sensation to light touch below the left knee chest tightness and dysphonic because of higher cholinergic activity triggered via inhibition of cholinesterase. However, patient has shown decreased sensation to light touch below the left knee due to the “neurotoxicity induced by fenthion pesticide” as it can diffuse into lipid layers of neuronal membrane easily. Therefore, results of plasma and red blood cell cholinesterase activity tests were within the normal range

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