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MEDICAL IMAGING QUESTION Would these radionuclides be good for PET imaging? What

ID: 1790307 • Letter: M

Question

MEDICAL IMAGING QUESTION

Would these radionuclides be good for PET imaging? What would be their advantages and disadvantages for PET imaging? Would these radionuclides be good for SPET imaging? What would be their advantages and disadvantages for SPECT imaging? Nuclide lodine-123 Nitrogen-13 Technicium-99m Fluorine-18 Copper-64 lodine-131 lodine-122 Emits Gamma Ray Positrorn Gamma Ray Positrorn Positrorn Gamma Ray Positron Half-Life 13.3 h 10 min 6 h 110 min 12.7 h 8 d 3.5 min Photon Energy (kev) 159 432 140 202 656 364 3100

Explanation / Answer

for PET imaging radionhuclides with very small life times ( of the order or 10 minutes) are used
hence
N-13, F-18, Cu-64, I-122 will be ideal for PET imaging
the disadvantes of tother radionuclides include non emssion of positron ( which is required for positron emiision tomography)

For SPET ( single photon emission tomography) radionuclides with half lifes of the order of a few tens of hours are used
hence
I-123, Tc-99, I-131 will be ideal candidates as these have half lives of a few hours to a few days
the disadvantage of other rasdionuclides are emission of positron and very low dosage ( as compared to SPET) requirements