Which of the following statement associated with your endodermal research papers

Question

Which of the following statement associated with your endodermal research papers is NOT correct? Select one:

a. Foxa proteins are required to make the endoderm competent to respond to FGF and form liver.

b. Mice lacking both Cdx1 and Cdx2 in the intestine exhibit a more pronounce phenotype then mice lacking only Cdx2.

c. Long-term loss of Cdx2 led to a partial conversion of the intestinal epithelium to a stomach-like nature.

d. Upregulation of Sox2 in the foregut leads to an inability to separate into the trachea and esophagus.

e. Foxa1 and Foxa2 are required for Pdx1 expression in the pancreatic buds.

Explanation / Answer

Answer: b- Mice lacking both Cdx1 and Cdx2 in the intestine exhibit a more pronounce phenotype then mice laking only Cdx2, because mice will exhibit a more pronounce phenotype when both Cdx1 and Cdx2 are lacking and these are expressed in both distal and proximal colon.

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