In this paper the authors demonstrated that susceptible E. coli clinical isolate

Question

In this paper the authors demonstrated that susceptible E. coli clinical isolates grew 3 times faster in urine compared to l) laboratory strains grown in urine, 2) clinical isolates grown in complex media, and 3) laboratory isolates grown in complex media. Why would the rapid growth of susceptible clinical isolates in urine lead to the increased ability to colonize the bladder successfully? (Hint: Think about the result of drinking coffee or beer?)

Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325821/

Explanation / Answer

To colonise the bladder the organisms need to be present and stay put in the bladder. If the growth rate is low, micturation (i.e urination, as also pointed by the hint, the result of drinking coffee or beer) might lead to removal of a lot of bacteria thus reducing the chances of stable colonisation of the bladder however if the isolates grow rapidly, even if most of the bacteria are removed during micturation the remaining few bacteria can grow rapidly and therefore continue to stably colonise the bladder

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