Question
E) one strand contains only purines and the other contains only pyrimidines. 11. Development of an inhibitor specific to telomerase of cancer cells would be useful to: A) increase cell division. B) kill cancer cells C) inhibit division of all body cells. D) inhibit ATP production E) inhibit proteins synthesis 12. The following statement is true about heterochromatin: A) Present in prokaryotes B) Does not exist in human C) Usually transcriptionally inactive D) Usually transcriptionally active. Refer to the following list of enzymes to answer the following questions. The answers may be used once, more than once, or not at all. A. helicase B. nuclease C. ligase D. DNA polymerase I E. primase 13. removes the RNA nucleotides from the primer and adds equivalent DNA nucleotides to the 3' end of Okazaki fragments Answer: 14. Covalently connects segments of DNA Answer: 15. The following statement is true about nucleosome: A) typically contains 147 nucleotide pairs. B) Histone protein core is surrounded by DNA C) Contains H2A D) Contains H2B E) All of the above statements are true. 16. The leading and the lagging strands differ in that A) the leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction. B) the leading strand is synthesized by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5' end. C) the leading strand is synthesized continuously, whereas the lagging strand is synthesized in short fragments that are ultimately stitched together.
Explanation / Answer
11. The answer is B. kill cancer cells.
Explaination:
The telomerase inhibitors might be useful agents that could selectively kill cancer cells while sparing normal cells.
Thus, the telomerase inhibitors will become a treatment option against cancer.
12. The answer is C. usually transcriptionally inactive.
Explaination:
The heterochromatin is highly condensed and so, transcriptionally inactive.
The heterochromatin is relatively poor in genes and its genes are not usually transcribed in a heterochromatic context.
13. The answer is D. DNA polymerase I
Explaination:
DNA polymerase I removes the RNA nucleotides from the primer and adds equivalent DNA nucleotides to the 3' end of okazaki fragments.
14. The answer is B. Ligases.
Explaination:
The ligase enzyme covalently connects the segments of DNA.
