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When we make a CRISPR mutation, what is the result and how is it normally fixed?

ID: 183081 • Letter: W

Question

When we make a CRISPR mutation, what is the result and how is it normally fixed?

EDIT: There is one correct answer. The options are listed a-i.

a. double stranded break; nucleotide excision repair.

b. abnormal basepair addition; basepair excision repair.

c. transversion; basepair excision repair.

d. double stranded break; synthesis dependent strand annealing.

e. synonymous mutants: basepair excision repair.

f. double stranded break; non homologous end joining.

g. abnormal basepair addition; SOS repair.

h. transversion; mismatch repair.

i. transition; non homologous end joining.

Explanation / Answer

Answer is B

CRISPR -Cas9 is a genome editing tool .It is a unique technology . It consist of 2 key molecules which introduce change in DNA . An enzyme called cas 9 , which acts as a molecular scissors , so that bits of DNA can be added or removed . And piece of RNA to guide -Cas9 to right part of genome.at this stage cell recognises the DNA is damaged and try to repair it

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