all AT&T; 5:23 PM * 60% Which of the following is a nonnucleoside inhibitor? zid
ID: 185119 • Letter: A
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all AT&T; 5:23 PM * 60% Which of the following is a nonnucleoside inhibitor? zidovudine stavudine nevirapine 3TC The double-stranded HIV DNA is inserted into the host DNA by O polymerase. O integrase invertase. O Nef. reverse transcriptase Which of the following is/are targe(s) of medicines for treating AIDS? O polymerase reverse transcriptase protease O matrix protein reverse transcriptase AND protease A vaccination is a good example of naturally acquired passive immunity O naturally acquired active immunity. O artificially acquired active immunity. O artificially acquired passive immunity The potential for hemolytic disease of the newborn occurs w OMaternal Rh+ cells enter an Rh-fetus Fetal Rh+ cells enter an Rh- mother Maternal Rh- cells enter an Rh+ fetus Fetal Rh- cells enter an Rh+ mother Fetal Rh+ cells enter an Rh+ mother Large quantities of antibodies that react to the second enery of antigen and lead to formaion of Serum sickness Delayed hypersensitivity Hemolytic disease of the newborn All of the choices are correctExplanation / Answer
1. Non-nucleoside reverse transcriptase inhibitors is nevirapine.
It blocks the synthesis of reverse transcriptase which helps to synthesise of single stranded RNA on DNA of human body by transcription so to block this enzyme is necessary to prevent further virus protein synthesis.
Hence option third nevirapine is correct.
2. Double stranded HIV DNA is inserted into the host DNA by the help of enzyme integrase.
Hence option second integrase is correct.
3. To treat the AIDS it is necessary to inhibit the synthesis of reverse transcriptase and protease enzymes because reverse transcriptase helps to virus protein synthesis on DNA strand. Protease is the enzyme which breaks down the protein into its smaller proteins. These smaller proteins combine with genetic material of human immunodeficiency virus to form new HIV virus. So to prevent this new virus replication it's necessary to block protease.
Hence last option is correct.
4. Vaccination is good example of naturally acquired active immunity. It is lifelong response of vaccination
Passive immunity is the process in which IgG antibodies provided to protect against infection.
Hence second option is correct.
5. Potential for the hemolytic diseases of the newborn occurs when the fetal Rh positive cells enters into the Rh negative mother.
Hence option second fetal Rh+ cells enter an Rh- mother.
6. Large quantities of antibodies that react to the second entry of antigen and lead to formation of antigen antibody complexes that deposit in basement membrane occurs in serum sickness. Serum sickness is delayed allergic response appearing 4 to 10 days after the exposure to antibiotics.
Hence first option is correct.
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