Spring, 2018 BTODCHEM 3343 NAME: Ctte is assignment is due at the start of class
ID: 186731 • Letter: S
Question
Spring, 2018 BTODCHEM 3343 NAME: Ctte is assignment is due at the start of class 10:10 am on Monday, Jan. 29, 2018. There are a total of 4 questions on this assignment. This assignment covers Hydrogen Bonding interactions and has you reviewing how to do simple pH calculations. 1. Using the molecule below which is a drug molecule albuterol answer questions 1a &1b, in this drawing all bonds, atoms and formal charges are shown. H2 CH3 CH 3 CH3 la. How many likely Hydrogen bond acceptors are on this molecule? What is the total number of Hydrogen bonding interactions these H-bond acceptor groups can make? Clearly circle all atoms or groups that are most likely to act as H-bond acceptors in this molecule. (5 points) lb. How many likely Hydrogen bond donors are on this molecule? What is the total number of Hydrogen bonding interactions these H-bond donor groups can make? Clearly place a triangle around all atoms that are most likely to act as H-bond donors in this molecule. (5 points)Explanation / Answer
Hi,
The hydrogen bond is a weak interaction formed between a donor and an acceptor. As the name suggests, hydrogen bond basically involves a hydrogen bond. The hydrogen bond donor is the one which is attached to a hydrogen atom and must be a small electronegative atom, like Oxygen, Nitrogen and fluoride ( -OH, -NH3, HF). These molecules can pull the electronegativity towards themselves an can creat a dipole. This attracts the lone pair of electrons from the H-bond acceptor. Hence the acceptor must also be an atom with high electronegativity. SO essentially its the O, N and F, which can act as both donors and acceptors depending on their location.
In the given image, the oxygen atoms can act as H-bond donors as well as donors. The lone N- acts of H-bond acceptor.
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